Armed with some knowledge from our pals at CrunchBase, I broke down the biggest US startup funding rounds from March 2025. I’ve included some extra info similar to business, firm description, spherical kind, founders, and complete fairness funding raised to additional the evaluation.
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11. Lila Sciences $200.0M
Spherical: Seed
Description: Cambridge-based Lila Sciences creates a scientific superintelligence platform and autonomous labs for all times sciences, chemistry, and supplies science. Based by Molly Gibson and Noubar Afeyan in 2023, Lila Sciences has now raised a complete of $200.0M in complete fairness funding and is backed by Normal Catalyst, Modi Ventures, Flagship Pioneering, March Capital, and Abu Dhabi Funding Authority.
Buyers within the spherical: Abu Dhabi Funding Authority, Altitude Life Science Ventures, ARK Enterprise Fund, Blue Horizon Advisors, Flagship Pioneering, Normal Catalyst, March Capital, Modi Ventures, State of Michigan Retirement System
Business: Synthetic Intelligence (AI), Life Science, Software program
Founders: Molly Gibson, Noubar Afeyan
Founding yr: 2023
Location: Cambridge
Whole fairness funding raised: $200.0M

10. Defend AI $240.0M
Spherical: Sequence F
Description: San Diego-based Defend AI is a deep-tech firm that focuses on creating AI-powered methods to boost the protection of service members and civilians. Based by Andrew Reiter, Brandon Tseng, and Ryan Tseng in 2015, Defend AI has now raised a complete of $1.0B in complete fairness funding and is backed by Andreessen Horowitz, Founder Collective, Riot Ventures, US Progressive Know-how Fund, and Bloomberg Beta.
Buyers within the spherical: Andreessen Horowitz, Cacti, Hanwha Aerospace, L3Harris Applied sciences, US Progressive Know-how Fund, Washington Harbour Companions
Business: Synthetic Intelligence (AI), Autonomous Automobiles, Drones, Machine Studying, Nationwide Safety
Founders: Andrew Reiter, Brandon Tseng, Ryan Tseng
Founding yr: 2015
Location: San Diego
Whole fairness funding raised: $1.0B

9. Celestial AI $250.0M
Spherical: Sequence C
Description: Santa Clara-based Celestial AI develops an optical interconnect expertise platform for knowledge middle and AI computing options. Based by David Lazovsky, Michelle Tomasko, and Preet Virk in 2020, Celestial AI has now raised a complete of $588.9M in complete fairness funding and is backed by BlackRock, Temasek Holdings, Tiger International Administration, US Progressive Know-how Fund, and Constancy.
Buyers within the spherical: AMD Ventures, BlackRock, Engine Ventures, Constancy, Koch Disruptive Applied sciences, Lip-Bu Tan, Maverick Silicon, Porsche Automobil Holding, Temasek Holdings, Tiger International Administration, Xora Innovation
Business: Synthetic Intelligence (AI), Knowledge Middle, Machine Studying, Semiconductor, Software program
Founders: David Lazovsky, Michelle Tomasko, Preet Virk
Founding yr: 2020
Location: Santa Clara
Whole fairness funding raised: $588.9M
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9. Epirus $250.0M
Spherical: Sequence D
Description: Torrance-based Epirus builds directed vitality and energy administration methods to unravel a number of the world’s most complicated issues. Based by Bo Marr, Grant Verstandig, Joe Lonsdale, John Tenet, Max Mednik, and Nathan Mintz in 2018, Epirus has now raised a complete of $537.4M in complete fairness funding and is backed by Nationwide Science Basis, StepStone Group, 8VC, Gaingels, and I Squared Capital.
Buyers within the spherical: 8VC, Anchor Capital GP, Centaurus Capital, Center15 Capital, Gaingels, Normal Dynamics Land Methods, Manhattan Enterprise Companions (MVP), NightDragon, Oppenheimer & Co., Protagonist, StepStone Group, T. Rowe Value, Washington Harbour Companions
Business: Aerospace, Equipment Manufacturing, Army, Software program
Founders: Bo Marr, Grant Verstandig, Joe Lonsdale, John Tenet, Max Mednik, Nathan Mintz
Founding yr: 2018
Location: Torrance
Whole fairness funding raised: $537.4M

8. Island $250.0M
Spherical: Sequence E
Description: Dallas-based Island gives an enterprise browser that enhances safety and productiveness by integrating important instruments. Based by Dan Amiga and Michael Fey in 2020, Island has now raised a complete of $810.0M in complete fairness funding and is backed by Sequoia Capital, Perception Companions, Cisco Investments, Coatue, and Canapi Ventures.
Buyers within the spherical: Canapi Ventures, Coatue, Cyberstarts, Georgian, Perception Companions, Sequoia Capital
Business: Cyber Safety, Enterprise Software program, Data Know-how, Internet Browsers
Founders: Dan Amiga, Michael Fey
Founding yr: 2020
Location: Dallas
Whole fairness funding raised: $810.0M

7. Flock Security $275.0M
Spherical: Sequence F
Description: Atlanta-based Flock Security offers end-to-end surveillance options to help regulation enforcement and communities. Based by Garrett Langley and Matt Feury in 2017, Flock Security has now raised a complete of $655.6M in complete fairness funding and is backed by Y Combinator, Andreessen Horowitz, Founders Fund, Spark Capital, and Kleiner Perkins.
Buyers within the spherical: Andreessen Horowitz, Bedrock, Founders Fund, Greenoaks, Kleiner Perkins, Matrix, Meritech Capital Companions, Sands Capital Ventures, Tiger International Administration, Y Combinator
Business: Manufacturing, Public Security, Safety, Sensor
Founders: Garrett Langley, Matt Feury
Founding yr: 2017
Location: Atlanta
Whole fairness funding raised: $655.6M
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6. Mercury $300.0M
Spherical: Sequence C
Description: San Francisco-based Mercury offers on-line banking options for startups and technology-focused companies. Based by Immad Akhund, Jason Zhang, and Max Tagher in 2017, Mercury has now raised a complete of $452.2M in complete fairness funding and is backed by Andreessen Horowitz, Sequoia Capital, Spark Capital, 500 International, and Coatue.
Buyers within the spherical: Andreessen Horowitz, Coatue, CRV, Marathon Administration Companions, Sequoia Capital, Spark Capital
Business: Banking, Monetary Providers, FinTech, Data Know-how, InsurTech
Founders: Immad Akhund, Jason Zhang, Max Tagher
Founding yr: 2017
Location: San Francisco
Whole fairness funding raised: $452.2M

5. Fleetio $450.0M
Spherical: Sequence D
Description: Birmingham-based Fleetio is a fleet upkeep administration software program that helps companies handle their fleet operations and optimize upkeep workflows. Based by Tony Summerville in 2011, Fleetio has now raised a complete of $620.1M in complete fairness funding and is backed by Endeavor Catalyst, Bossa Make investments, Elephant, and Goldman Sachs Options.
Buyers within the spherical: Elephant, Goldman Sachs Options
Business: Automotive, Fleet Administration, SaaS, Software program
Founders: Tony Summerville
Founding yr: 2011
Location: Birmingham
Whole fairness funding raised: $620.1M

4. Nerdio $500.0M
Spherical: Sequence C
Description: Chicago-based Nerdio gives cloud options to streamline IT administration, specializing in Microsoft Azure and digital desktop optimization. Based by Joseph Landes and Vadim Vladimirskiy in 2016, Nerdio has now raised a complete of $625.0M in complete fairness funding and is backed by Normal Atlantic, StepStone Group, Lead Edge Capital, Updata Companions, and MK Capital.
Buyers within the spherical: Normal Atlantic, Lead Edge Capital, StepStone Group
Business: Cloud Computing, Data Providers, Data Know-how, Software program
Founders: Joseph Landes, Vadim Vladimirskiy
Founding yr: 2016
Location: Chicago
Whole fairness funding raised: $625.0M
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3. X (previously Twitter) $1.0B
Spherical: Enterprise
Description: Bastrop-based X is a social networking platform that permits its customers to ship and browse microblogs. Based by Biz Stone and Jack Dorsey in 2006, X (previously Twitter) has now raised a complete of $12.1B in complete fairness funding and is backed by Andreessen Horowitz, Sequoia Capital, Perception Companions, Union Sq. Ventures, and Sluggish Ventures.
Buyers within the spherical: 1789 Capital, Bossa Make investments, Darsana Capital Companions, Elon Musk, Manhattan Enterprise Companions (MVP)
Business: Running a blog Platforms, Social Media, Social Community, Web3
Founders: Biz Stone, Jack Dorsey
Founding yr: 2006
Location: Bastrop
Whole fairness funding raised: $12.1B

2. Anthropic $3.5B
Spherical: Sequence E
Description: San Francisco-based Anthropic is an AI analysis firm that focuses on the protection and alignment of AI methods with human values. Based by Daniela Amodei, Dario Amodei, Jack Clark, Sam McCandlish, and Tom Brown in 2021, Anthropic has now raised a complete of $12.9B in complete fairness funding and is backed by Normal Catalyst, Menlo Ventures, Lightspeed Enterprise Companions, Bessemer Enterprise Companions, and Google.
Buyers within the spherical: Bessemer Enterprise Companions, Cisco Investments, D1 Capital Companions, Constancy, Normal Catalyst, Jane Avenue Capital, Lightspeed Enterprise Companions, Menlo Ventures, Salesforce Ventures
Business: Synthetic Intelligence (AI), Generative AI, Data Know-how, Machine Studying
Founders: Daniela Amodei, Dario Amodei, Jack Clark, Sam McCandlish, Tom Brown
Founding yr: 2021
Location: San Francisco
Whole fairness funding raised: $12.9B

1. OpenAI $40.0B
Spherical: Enterprise
Description: San Francisco-based OpenAI creates synthetic intelligence applied sciences to help with duties and supply help for human actions. Based by Andrej Karpathy, Durk Kingma, Elon Musk, Greg Brockman, Ilya Sutskever, John Schulman, Pamela Vagata, Sam Altman, Trevor Blackwell, Vicki Cheung, and Wojciech Zaremba in 2015, OpenAI has now raised a complete of $57.6B in complete fairness funding and is backed by Andreessen Horowitz, Y Combinator, NVIDIA, Sequoia Capital, and HSBC.
Buyers within the spherical: Altimeter Capital, Coatue, Microsoft, SoftBank, Thrive Capital
Business: Synthetic Intelligence (AI), Generative AI, Machine Studying, Pure Language Processing, SaaS
Founders: Andrej Karpathy, Durk Kingma, Elon Musk, Greg Brockman, Ilya Sutskever, John Schulman, Pamela Vagata, Sam Altman, Trevor Blackwell, Vicki Cheung, Wojciech Zaremba
Founding yr: 2015
Location: San Francisco
Whole fairness funding raised: $57.6B
The TechWatch Media Group viewers is driving progress and innovation on a world scale. With its regional media properties (NYC Tech, LA Tech, London Tech)TechWatch Media Group is the freeway for expertise and entrepreneurship. Learn how to accomplice with us to drive a return in your advertising funding right here.